Table of Contents


Contributors

Preface

SECTION I: BASIC PRINCIPLES AND CONSIDERATIONS OF RATIONAL CHEMOTHERAPY AND MOLECULAR TARGETED THERAPY

1 Biologic and Pharmacologic Basis of Cancer Chemotherapy

2 Biologic Basis of Molecular Targeted Therapy

3 Systematic Assessment of the Patient With Cancer and Consequences of Treatment

4 Selection of Treatment for the Patient With Cancer

SECTION II: CHEMOTHERAPY AND MOLECULAR TARGETED THERAPY OF HUMAN CANCER

5 Carcinomas of the Head and Neck

6 Carcinoma of the Lung

7 Carcinomas of the Gastrointestinal Tract

8 Carcinomas of the Pancreas, Liver, Gallbladder, and Bile Ducts

9 Carcinoma of the Breast

10 Gynecologic Cancer

11 Urologic and Male Genital Cancers

12 Kidney Cancer

13 Thyroid and Adrenal Carcinomas

14 Melanomas and Other Cutaneous Malignancies

15 Primary and Metastatic Brain Tumors

16 Soft-Tissue Sarcomas

17 Bone Sarcomas

18 Acute Leukemias

19 Chronic Leukemias

20 Myeloproliferative Neoplasms and Myelodysplastic Syndromes

21 Hodgkin Lymphoma

22 Non-Hodgkin Lymphoma

23 Multiple Myeloma, Other Plasma Cell Disorders, and Primary Amyloidosis

24 Metastatic Cancer of Unknown Origin

25 HIV-Associated Malignancies

SECTION III: SUPPORTIVE CARE OF PATIENTS WITH CANCER

26 Side Effects of Chemotherapy and Molecular Targeted Therapy

27 Infections: Etiology, Treatment, and Prevention

28 Transfusion Therapy, Bleeding, and Clotting

29 Oncology Emergencies and Critical Care Issues: Spinal Cord Compression, Cerebral Edema, Superior Vena Cava Syndrome, Anaphylaxis, Respiratory Failure, Tumor Lysis Syndrome, Hypercalcemia, and Bone Metastasis

30 Malignant Pleural, Peritoneal, and Pericardial Effusions and Meningeal Infi ltrates

31 Cancer Pain

32 Emotional and Psychiatric Problems in Patients with Cancer

SECTION IV: CHEMOTHERAPEUTIC AND MOLECULAR TARGETED AGENTS AND THEIR USE

33 Classification, Use, and Toxicity of Clinically Useful Chemotherapy and Molecular Targeted Therapy

Appendix A: Surface Area of Adults from Height and Mass

Appendix B: Surface Area of Children from Height and Mass